Tissue engineering of functional articular cartilage: the current status
نویسندگان
چکیده
منابع مشابه
bovine articular cartilage decellularized matrix as a scaffold for use in cartilage tissue engineering
extracelllar matrix (ecm) materials from mammalian tissues have been broadly used for tissue engineering for animal models. while decellularization of tissues such as bladder, heart valve, knee meniscus and tendon has been performed, there are a few reports for articular cartilage. in this study we aimed to develop a technique to decellularize bovine articular cartilage as a biological construc...
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Damage to cartilage is of great clinical consequence given the tissue's limited intrinsic potential for healing. Current treatments for cartilage repair are less than satisfactory, and rarely restore full function or return the tissue to its native normal state. The rapidly emerging field of tissue engineering holds great promise for the generation of functional cartilage tissue substitutes. Th...
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Efforts to expand treatment options for articular cartilage repair have increasingly focused on the implantation of cell polymer constructs. Primary cells cultured from perichondrium, a chondrogenic tissue, were found to survive in vitro within a biodegradable porous polylactic acid matrix. These perichondrocyte-polylactic acid composite grafts were then implanted within osteochondral defects d...
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OBJECTIVE The purpose of this article is to review the current understanding of the MRI appearance of articular cartilage and its relationship to the microscopic and macroscopic structure of articular cartilage, the optimal pulse sequences to be used in imaging, the appearance of both degenerative and traumatic chondral lesions, the appearance of the most common cartilage repair procedures, and...
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Cartilage is an avascular connective tissue found in many locations in the body, such as, in the joints between the bones, rib cage, ear, nose and intervertebral discs. Cartilage plays a vital role in our body by working as a cushion between joints so that rubbing of bones against each other is prevented. It also holds some bones together, for instance, rib cartilage, and makes the area shock-p...
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ژورنال
عنوان ژورنال: Cell and Tissue Research
سال: 2011
ISSN: 0302-766X,1432-0878
DOI: 10.1007/s00441-011-1243-1